JOPE TECHNOLOGY

SMB chromatography is a continuous separation technique that enhances efficiency and reduces solvent consumption compared to traditional batch chromatography. In SMB, multiple columns are arranged in a loop, and the positions of the inlet and outlet streams are periodically shifted to simulate the countercurrent movement of the stationary phase. This continuous operation allows for higher throughput and improved separation of components.

SF-SMB combines the principles of SMB chromatography with supercritical fluids, typically supercritical carbon dioxide, as the mobile phase. This integration offers several advantages:

• Enhanced Solubility: Supercritical fluids can dissolve a wide range of compounds, improving separation efficiency.

• Tunability: The solvating power of supercritical fluids can be adjusted by modifying temperature and pressure, allowing for precise control over the separation process.

• Environmental Benefits: Utilizing supercritical CO₂ reduces the need for organic solvents, making the process more environmentally friendly.

SMB and SF-SMB technologies are employed across various industries:

• Pharmaceuticals: For the separation of chiral compounds and purification of active pharmaceutical ingredients.

• Petrochemicals: Used in the separation of isomers and purification of chemical intermediates.

• Food Industry: Applied in the purification of sugars and other food additives.

• Fine Chemicals: Employed in the production of high-purity specialty chemicals.

Jope Technology provides a comprehensive range of SMB solutions tailored to various industry requirements:

• Standard SMB Systems: Designed for efficient separation of binary mixtures, suitable for large-scale industrial applications.

• SF-SMB Systems: Integrating supercritical fluid technology for enhanced separation performance, ideal for thermally sensitive compounds.

• Customizable SMB Solutions: Offering flexibility in design to meet specific process needs, including multi-component separations and integration with existing production lines.

Our products are engineered to deliver high purity, yield, and productivity, ensuring optimal performance across applications.